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We are always working! One earlier meta-analysis [9] assessed the performance of GEC. 3, pp. Thyroid hormone replacement after thyroid lobectomy. Use cold pack for transport. We aimed to evaluate the diagnostic performance of Afirma gene expression classifier (GEC) for the indeterminate thyroid nodules (ITNs). Ambient, refrigerated. Our present data revealed that the pooled NPV of GEC was not as high as previous studies [7, 9, 32]. I get your point & understand the need for this order for you. Correlation between overall surgical pathologically cases and GEC results (N=1617). Storage and Transportation. MetaDisc software was used to investigate the pooled sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), diagnostic odds ratio (DOR), and summary receiver operating characteristic (SROC) curves. In the TBSRTC, the adenomatoid nodule is divided into category III or category IV [1]. I will call back on Monday and be more insistent. Molecular testing is evolving quickly and becoming the standard in assessing need for and type of surgery for patients with indeterminate thyroid nodules. The high sensitivity makes it probable to rule out malignant nodules. R. Harrell and D. Bimston, Surgical utility of afirma: effects of high cancer prevalence and oncocytic cell types in patients with indeterminate thyroid cytology, Endocrine Practice, vol. How often do you hear someone say, "I wish I had more hours in a . Therefore, the superiority of the GEC test lies in ruling-out of malignancy (higher sensitivity) and the ThyroSeq is a better test of ruling-in thyroid neoplasm (higher specificity). I am a one-woman show, so turnaround time may change at any time. To some extent, ultrasound-guided FNA with on-site cytopathology improves both adequacy and accuracy of preoperative diagnoses in ITNs. Approximately 15 to 30% of thyroid nodules evaluated by fine-needle aspiration (FNA) were classified as indeterminate; the accurate diagnostic molecular tests of these nodules remain a challenge. This is "ThyroSeq" by Stacey Rosenberg on Vimeo, the home for high quality videos and the people who love them. [emailprotected] 866-604-6774 NOTICE - Many of our factories are experiencing extended production times. Maecenas nec odio et ante tincidunt tempus. Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology. Drones can help significantly reduce turnaround times by making it much easier and quicker for inspectors to collect visual data for inspection purposes. Bethesda System for Reporting Thyroid Cytopathology, Pharmacological Approaches to Obesity Treatment, Preserving Mental Health for Those Living with Diabetes, How to Manage Overlapping Diabetes and Osteoporosis, Adrenal Masses and Type 2 Diabetes: Proceed with Caution, Meeting Highlights: Thyroid Cancer Treatment, Bone Disorders, and More, Transgender Medicine: From Consult to Surgery. Lithwick-Yanai G, Dromi N, Shtabsky A, et al. 789796, 2015. Etiam ultricies nisi vel augue. In the case of plant turnarounds needed for regular inspections and maintenance, these can be anticipated well in advance and thoroughly planned for since they are usually required periodicallyannually, bi-annually, or on some other time frame, as mandated by law in many instances. If you have a related question, please click the "Ask a related question" button in the top right corner.The newly created question will be automatically linked to this question. All conflicts were resolved through consensus within the groups. High Point Central Athletics, 966970, 2015. thyroseq turn around time. This methodology is now included in recommendations of leading clinical guidelines, including those from the American Thyroid Association (ATA), National Comprehensive Cancer Network and UpToDate.. Meanwhile, we checked the references of included literatures to identify additional relevant publications. 705715, 2012. Sosa JA, et al. J. Y. Kwak, I. Jung, J. H. Baek et al., Thyroid imaging reporting and data system for ultrasound features of thyroid nodules: multicentric korean retrospective study, Korean Journal of Radiology, vol. Data goes from 2013-01-01 to 2014-04-15. from publication: Agent-based Truck Appointment System for Containers Pick-up Time Negotiation | Congestion in . F. M. Girardi, M. B. Barra, and C. G. Zettler, Papillary thyroid carcinoma: does the association with Hashimoto's thyroiditis affect the clinicopathological characteristics of the disease? Brazilian Journal of Otorhinolaryngology, vol. Fixed samples: Room temperature and shipped routinely, 48-72 hours for all (fluid/brushing, Urine and FNA cytology specimens), Preparation of slide(s) from submitted urine sample utilizing liquid basedtechniques to include ThinPrep and cytospin for microscopic interpretation. Nullam quis ante. He is also chairman of Pakistan Psychiatric Research Centre & a Board member of Fountain House Lahore. 20, no. In the last decade, some studies [810] have evaluated its effects on ITNs but the results were inconsistent, probably due to the rates of indeterminate biopsy result varying among the hospitals and tertiary centers [11]. Federal Contract Opportunity for Q301--Cytopathology and ThyroSeq Testing 36C24421Q0574. Download scientific diagram | Truck Turnaround Time, Queueing time, and Service Time. We checked the database and included 18 newly published studies to provide a more comprehensive analysis on the diagnostic performance of GEC and discuss its role in decision-making process of thyroid surgery. Ambient, refrigerated. 1, p. 16, 2019. The speaker is interested in diabetes and womens health, the goal is to invent technical solutions for better healthcare. Yes! 151, no. The first person told me it usually takes 2-3 weeks and last week I was told 4 weeks. 3. Needle rinse and designated pass into Cytolyt, ethanol or formalin for cell block preparation as needed. As federal and state dollars flow to districts and individual schools charged with embarking upon transformative change efforts, districts must adopt a laser-sharp focus on assessing turnaround leaders' performance . 74.6k members in the step1 community. Download scientific diagram | Truck Turnaround Time, Queueing time, and Service Time. Molecular testing is increasingly becoming the new standard of care in evaluating thyroid nodules for the presence of cancer. For specimens in which a hematopoietic disorder cannot be excluded or Lymphoma is suspected additional FNA material to be collected in RPMI for flow cytometry testing All jars, tubes and slides must be labeled with two (2) patient identifiers clearly written and matching exactly with the specimen identifiers and specimen labeling on the accompanying requisition, 30 ml Cytolyt tube or 1-2, Air-dried direct smears in cardboard holder And/or2-4, Direct smears (ethanol fixed) in coplin jar. 122, no. Time it Takes to Start Responding, Not the Time it takes to Output the Response. Since the most benign nodules with GEC-suspicious results are follicular adenomas, benign follicular nodules and adenomatoid nodules, it is essential to combine other molecular markers to improve the specificity of GEC. An easy way to think of turnaround time is the time from the moment a request is made or a process is started to the time when the request is fulfilled or the process is complete. We screened the studies following the process that was illustrated in Figure 1. The gold reference standard relied on the histopathologic results diagnosis from thyroidectomy surgical specimens. Hang, W. H. Westra, D. S. Cooper, and S. Z. Ali, The impact of noninvasive follicular thyroid neoplasm with papillary-like nuclear features on the performance of the Afirma gene expression classifier, Cancer Cytopathology, vol. Browse the use examples 'turnaround time ,' in the great English corpus. Embase search was done using the following keywords (Thyroid Nodule/diagnosis[Mesh] OR Thyroid Nodule/surgery[Mesh]) AND (gene expression classifier OR GEC). Benign nodules include follicular carcinoma and oncocytic adenoma. And 15ml Cytolyt, ethanol or formalin jar for needle rinse/cellblock. dept. 21,276 Turnaround Time jobs available on Indeed.com. Pathological diagnoses at resection of Afirma results with cytological subtypes (N=225). Ambient, are to be refrigerated after 1hr of collection. If the above conditions are met, there is a 79-93% success rate of testing. Sample: ID Created_EST Transport_Arrival_EST Exit_EST What is the completion time, turnaround time, and waiting time for First Come First Serve, Round Robin, Shortest Process Next, Shortest Remaining Time, Highest Response Ratio Next, and Multilevel Feedback for these set of arrival and service times? 27, no. Please include the Ray ID (which is at the bottom of this error page). All authors read and approved the final manuscript. 22, no. 5, pp. S. Chaudhary, Y. Hou, R. Shen, S. Hooda, and Z. Li, Impact of the afirma gene expression classifier result on the surgical management of thyroid nodules with category III/IV cytology and its correlation with surgical outcome, Acta Cytologica, vol. Methods. Performance of cytological subtypes indeterminate cases with GEC results (N=1628). M. Borowczyk, E. Szczepanek-Parulska, M. Olejarz et al., Correction to: evaluation of 167 gene expression classifier (GEC) and ThyroSeq v2 diagnostic accuracy in the preoperative assessment of indeterminate thyroid nodules: bivariate/HROC meta-analysis, Endocrine Pathology, vol. Please refer to Student Health Center's Hours of Operation for the most up to date information. Apply to Proofreader, Sales Representative, Customer Specialist and more! Maecenas tempus, tellus eget condimentum rhoncus, sem quam semper libero, sit amet adipiscing sem neque sed ipsum. P. Aragon Han, M. T. Olson, R. Fazeli et al., The impact of molecular testing on the surgical management of patients with thyroid nodules, Annals of Surgical Oncology, vol. Diff-Quik staining (if needed): Air-dried direct smears 1-2 slides with at least 200-300 cells are required. ; Burst time of a process can not be known in advance before executing the process. A systematic review [30] which evaluated the methods of studies of GEC and concluded the most common methodologic drawback was lack of reference standard diagnosis analyses to unexcised ITNs with GEC-benign results, which resulted in overestimating the specificity. 4. Cloudflare monitors for these errors and automatically investigates the cause. Steward D. Clinical Validation of ThyroSeq V3 Performance in Thyroid Nodules with Indeterminate Cytology: A Prospective Blinded Multi-Institutional Validation Study. 30, pp. The SROC curve has been shown in Figure 4 with prediction and confidence contours. This site uses cookies to improve user experience and performance. Storage and Transportation. Since the false negative and true negative values of two included studies [17, 27] were 0, the original data of these two studies was dropped by the MetaDisc software. 2019. We wish to express our warm thanks to those who have contributed to the study. 120, no. R. R. Lastra, M. R. Pramick, C. J. Crammer, V. A. LiVolsi, and Z. W. Baloch, Implications of a suspicious afirma test result in thyroid fine-needle aspiration cytology: an institutional experience, Cancer Cytopathology, vol. Hi all, I'm in need of some help to make sure about turnaround time for ordering a model 3 right now. Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science Conference. 2018. The most common application of molecular testing in thyroid nodule assessment is to guide care for patients with indeterminate nodules. We got 5290 patients assessed by FNA; 3390 nodules were categorized as ITNs, 2889 of which underwent gene expression classifier finally. Bihui Pan took charge of data statistics and Li Xu extracted the parameters from each study. Did you know that our custom face masks turnaround time is 2 to 3 days max? 2018. ; Burst time of a process can not be known in advance before executing the process. 10-14 days is a typical turnaround time for a medium-low complexity projects. Sustainable Development PerformanceRailingsTonnage received increased from 68.52 Mt in 2012 to 70.8Mt in 2013, the first time coal deliveries exceeded the 70 million mark.The key performance indicators were also exceeded as Train Turnaround Time (TTT) reached a record of 03:08. The benign thyroid nodules proved by surgical resection are follicular adenoma, benign follicular nodule and adenomatoid nodule, etc. Anal Specimen: Brushing collected in Preservcyt Jaror or CytoLyt tube, All jars, tubes and slides must be labeled with two (2) patient identifiers clearlywritten and matching exactly with the specimen identifiers and specimen labelingon the accompanying requisition, Sterile plastic container or Cytolyt tube or Preservcyt jar This includes ordering the necessary germline genetic counseling and testing, and tumor marker tests that inform the need for additional tests, such as imaging studies to evaluate for metastases. I didn't want to be pushy if this was normal but it doesn't seem right. 22, no. Clinical Validation of the Afirma Genomic Sequencing Parathyroid Classifier. Primeweld Cut60 User Manual, A total of 18 studies involving 5290 patients with 3290 cases of ITNs were included. Learn more I got my invite on 2/22 But didn't put in an order since I was worried I wouldn't get it on time before my vacation. Since the I2 values of the sensitivity, specificity, PLR, and NPV were more than 50%, we conducted the metaregression analysis (inverse variance weights) to investigate the sources of heterogeneity. Most nodules with benign pathological results and well-differentiated PTC are proliferated from thyroid follicular cells. cytology smears. BRAF mutation has low prevalence in the FN/SFN and AUS/FLUS while high in the SM cytology thyroid lesions [42, 43]. 917924, 2016. Impact of the Multi-Gene ThyroSeq Next-Generation Sequencing Assay on Cancer Diagnosis in Thyroid Nodules with Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Cytology. Moved Permanently. First, we failed to obtain the pathologic diagnosis of all the resected nodules, due to the missed original contents in some of the included studies. [email protected] 866-604-6774 NOTICE - Many of our factories are experiencing extended production times. 3, pp. His role in international psychiatry is highlighted by his current position as President of World Psychiatric Association (WPA). 8, pp. Evaluation of a Two-Year Routine Application of Molecular Testing of Thyroid Fine-Needle Aspirations Using a Seven-Gene Panel in a Primary Referral Setting in Germany. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer. 125, no. 5. Several original articles missed part of the detailed pathological results of surgical samples, just described surgical results as benign or malignant. For the guys that sometime submit to BGS, how long does it usually take for a 10 day service level entry to be logged into their system and does their 10 day clock start when it's logged? Chin PD, et al. demonstrated that there were no significant changes in surgery rates and malignant prevalence by comparing pre-Afirma and post-Afirma cases [12]. This period of time is often commonly called downtime, a planned outage, or a plant turnaround. He is part of Early Career Psychiatrists (ECPs) section of World Psychiatry Association (WPA). Aenean vulputate eleifend tellus. Thyroid. Time used by an airtanker or helitanker to reload and return to the fire. He deals with schizophrenia & related disorders, psychopharmacology, clozapine-related DRESS syndrome, evidence-based medicine, systematic reviews and allied topics. Patients selection for surgery may affect both accuracy and clinical applicability of the test. Preparation of slide(s) from submitted fluid or brushing specimens utilizing liquid based techniques to include ThinPrep or cytospin with Cell Block preparation (as needed) and direct smears for microscopic interpretation. The most surgical malignant lesions are cvPTCs and fvPTCs. Number of Processes that are Quality products made for your protection quickly! P. Santhanam, R. Khthir, T. Gress et al., Gene expression classifier for the diagnosis of indeterminate thyroid nodules: a meta-analysis, Medical Oncology, vol. I know this is a PSA board, but I have much more faith in you guys than those yahoos over on the BGS board. Hi, Thank you for writing to us here about the order. Findings presented at the 2017 ATA meeting demonstrated the tests ability through additional classifiers to accurately identify the BRAF V600E mutation, parathyroid tissue, and MTC. Subsequent classifiers have been introduced, which also combine genomic data and machine learning to identify benign nodules. Knowing that a patient has MTC before surgery can enable the surgeon to more appropriately plan. This period of time is often commonly called downtime, a planned outage, or a plant turnaround. It says results in less than 24 hours - curious what the turnaround time is like these Yesterday, I placed 16 things on my to-do list. 205210, 2016. Did you know that our custom face masks turnaround time is 2 to 3 days max? J. P. Abeykoon, L. Mueller, F. Dong, A. V. Chintakuntlawar, J. Paludo, and R. Mortada, The effect of implementing gene expression classifier on outcomes of thyroid nodules with indeterminate cytology, Hormones and Cancer, vol. Full details here FNAC is a reliable method with good sensitivity and specificity [23]. After underwent surgery, all samples were proved to be either benign or malignant. Cancer Cytopathol. 40, no. The test uses mRNA expression data obtained through microarray analysis and machine learning to identify benign nodules among those previously classified as indeterminate. If you anticipate needing in-depth engineering work during a planned outage(or are having a turnaround just for this reason), here are some steps you can take to try and avoid unanticipated delays: Although plant turnarounds can be planned well in advance, this advance scheduling also needs to include communication with other departments in a plant or company. The Impact of Benign Gene Expression Classifier Test Results on the EndocrinologistPatient Decision to Operate on Patients with Thyroid Nodules with Indeterminate Fine-Needle Aspiration Cytopathology. Burst Time- Burst time is the amount of time required by a process for executing on CPU. Fluid Collection: 1ml-200ml fresh or fixed fluid The time between discharge of the patient and the completion of that patient's medical record. 30, no. If a fresh FNA sample collected into ThyroSeqPreserve is not available or has failed ThyroSeq testing, cytology smears can be submitted for testing. The area under the curve (AUC) is 0.73. [email protected] (817) 735-2465 Find out what is the most common shorthand of TurnAround Time on Abbreviations.com! 1, pp. I got my invite on 2/22 But didn't put in an order since I was worried I wouldn't get it on time before my vacation. These rates are similar in accuracy to those of a benign cytopathology result. National Comprehensive Cancer Network. 163, no. Digital pathology is becoming a relevant tool in healthcare, industrial and research sectors to reduce the saturation of pathology departments and improve the productivity of pathologists by increasing diagnostic accuracy and reducing turnaround times. I'll have this checked & help you with the details. Diff-Quik and Papanicolau (Pap) stained smears are acceptable It is up to the sending institution to save digital images of the slides prior to sending for testing. The pooled sensitivity of GEC is 95.5% (95% CI 93.5%97.0%, I2 value 65.0%, p < 0.001), the pooled specificity is 22.1% (95% CI 19.4%-24.9%, I2 value 89.1%, p < 0.001), the PLR is 1.167 (95% CI 1.0881.252, I2 value 77.5%, p < 0.001), the NLR is 0.285 (95% CI 0.1990.410, I2 value 0.00%, p= 0.778), the NPV is 88.2% (95% CI 0.8330.921, I2 value 41.1%, p < 0.001), the PPV is 44.3% (95% CI 0.4160.471, I2 value 65.0%, p < 0.001), and the DOR is 5.25 (95% CI 3.428.04, I2 value 0.00%, Q 9.42, p=0.855). The first version of ThyroSeq was launched for clinical use at the University of Pittsburgh Medical Center as a seven-gene panel (ThyroSeq v0) in April of 2007. Hi all, I'm in need of some help to make sure about turnaround time for ordering a model 3 right now. 364369, 2014. Hegedus L 2004 Clinical practice. Pre-operative knowledge of MTC enables the treating physician to anticipate potential complications such as life-threatening hypertension that can accompany MTC in the setting of multiple endocrine neoplasia type 2. This thread has been locked. When the turnaround begins, its crucial that everyone involved knows their job and is moving as efficiently as possible through their work. Moon, and J. Y. Kwak, Diagnosis and management of small thyroid nodules: a comparative study with six guidelines for thyroid nodules, Radiology, vol. In one test, ThyroSeq Classifier: Confidently rules out cancer and prevents unneeded surgeries in 61-67% of patients with indeterminate cytology nodules 2-8. Cloudflare monitors for these errors and automatically investigates the cause. 3, pp. 30 ml Cytolyt tube or 1-2, Air-dried direct smears in cardboard holder And/or 2-4, Direct smears (ethanol fixed) in coplin jar. However, the malignancy risk in TBSRTC categories III and IV ranges between 5% and 30% after surgery [5]. The thyroid imaging reporting and data system. Nulla consequat massa quis enim. 11, pp. Lab 949-824-6361 949-824-3033 (fax) Student Health Center Laboratory is open during Student Health Center's hours of operation. Fluid Collection: 1ml-200ml fresh or fixed fluid Nipple Discharge: 1-2 direct smears, spray fixed Brushing Sample: Collected in 30 ml Cytolyt tube And/or Direct smears immediately spray fixed or fixed in ethanol and brush collected in ethanol or Cytolyt tube Anal Specimen: Brushing collected in Preservcyt Jaror or CytoLyt tube All jars, tubes and slides must be labeled with two (2) patient . Fayetteville Nc Tornado 2021, 12, pp. I attached table DDL scripts to populate two tables with some sample records. E. S. Cibas and S. Z. Ali, The 2017 bethesda system for reporting thyroid cytopathology, Thyroid, vol. The histopathological results of the thyroidectomy specimen were the reference standard for the determination of benign or malignant nodules. test utilizes next-generation sequencing to analyze DNA and RNA of 112 thyroid-related genes for four main classes of molecular alterations, including mutations, gene fusions, copy number alterations, and gene expression alterations, The results are processed by a unique Genomic Classifier (GC) and reported as Positive or Negative, Confidently rules out cancer and prevents unneeded surgeries in 61-67% of patients with indeterminate cytology nodules. If delay of more than 24 Hours is expected add an equal amount of Cytolyt or ethanol to the sample. What is the completion time, turnaround time, and waiting time for First Come First Serve, Round Robin, Shortest Process Next, Shortest Remaining Time, Highest Response Ratio Next, and Multilevel Feedback for these set of arrival and service times? Shop www.kentegrads.com Simpler projects are quicker, more complex projects take longer. He has served the Royal College of Psychiatrists UK as Deputy & Associate Registrar & Chairman of West Midlands Division of the College. 892899, 2011. With hundreds of customers in over 50 countries in Power Generation, Oil & Gas, Chemicals, Maritime, Infrastructures & Utilities, and Public Safety, Flyability has pioneered and continues to lead the innovation in the commercial indoor drone space. Summary receiver operating characteristic, Atypia of undetermined significance/follicular lesion of undetermined significance, Follicular neoplasm or suspicious for follicular neoplasm. Phasellus viverra nulla ut metus varius laoreet. 5, pp. 2. Apply to Proofreader, Sales Representative, Customer Specialist and more! Use cold pack fortransport if necessary. During planned downtimes, these are some of the most common types of turnaround work: In any setting, turnaround time equals money. (a) the total waiting time for a process to finish execution (b) the total time spent in the ready queue (c) the total time spent in the running queue Solution for Turnaround time It is the a. And 15ml Cytolyt, ethanol or formalin jar for needle rinse/cellblock. Guan H, et al. The Web's largest and most authoritative acronyms and abbreviations resource. Quisque rutrum. In addition to refining physicians ability to resolve indeterminate thyroid nodules, molecular testing will likely increase in use to inform optimal therapy and measure therapy response, among other uses. Use cold pack for transport if necessary. How to say ThyroSeq in English? For cytology smear sample submission: 1-2 slides with at least 200-300 cells are required. The field of digital histopathology has seen incredible growth in recent years. Eszlinger M et al. Posted by: Category: Sem categoria . W. L. Sacks, S. Bose, Z. S. Zumsteg et al., Impact of Afirma gene expression classifier on cytopathology diagnosis and rate of thyroidectomy, Cancer Cytopathology, vol. Davor Mucic is a psychiatrist from Denmark with special interest in use of technology in provision of mental health care. From second table I need to calculate TAT - Turnaround time. E. Brauner, B. J. Holmes, J. F. Krane et al., Performance of the afirma gene expression classifier in hrthle cell thyroid nodules differs from other indeterminate thyroid nodules, Thyroid, vol. However, adding the BRAF V600E mutation to GEC did not improved the diagnostic sensitivity and specificity [44]. 10, pp. If a fresh FNA sample collected into ThyroSeqPreserve is not available or has failed ThyroSeq testing, cytology smears can be submitted for testing. 7, no. The performance of GEC could range widely between tertiary care facilities and comprehensive hospitals [9]. 11, pp. Hi all, I'm in need of some help to make sure about turnaround time for ordering a model 3 right now. The summary of final histopathologic subtypes of all samples are available in Table 5 (N=960). It suggests less than 2 hours to fully prepare the aircraft for the journey to Dubai after landing at Bali. catahoula leopard dog intelligence ranking; reginos pizza nutrition facts; vintage carlsberg glasses; average age of american cruise line passengers. Lorem ipsum dolor sit amet, consectetuer adipiscing elit. If delay of more than 24 Hours is expected add an equal amount of ethanol (50%) or Cytolyt to the sample (urine samples for microbiology/culture are to remain unfixed/fresh). 19, no. 260, no. D. S. Cooper, G. M. Doherty, B. R. Haugen et al., Revised American thyroid association management guidelines for patients with thyroid nodules and differentiated thyroid cancer, Thyroid, vol. Y. E. Nikiforov, S. E. Carty, S. I. Chiosea et al., Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by thyroseq V2 next-generation sequencing assay, Cancer, vol. 403408, 2017. In a clinical validation study, Lithwick-Yanai et al reported that the test had a sensitivity of 74% for Bethesda III and IV nodules. 11, pp. 141, no. G. Harrison, J. The forest plots exhibit the pooled sensitivity, specificity, PLR, NLR, diagnostic score, and DOR (Figures 2(a)2(e)). The ThyroSeq Genomic Classifier is available in the United States through Sonic Healthcare USA.