If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Losartan/hydrochlorothiazide, sold under the trade name Hyzaar among others, is a combination medication used to treat high blood pressure when losartan is not sufficient. 2.1 General Considerations. The usual starting dose of losartan monotherapy is 50 mg PO once daily, with 25 mg PO recommended for patients with intravascular volume depletion (e.g., patients treated with diuretics) or a history of hepatic impairment. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This product may contain inactive ingredients, which can cause allergic reactions or other problems. The usual dosage is around 0.7 mg/kg of body weight taken once per day. Severe renal dysfunction (CrCl less than 30 mL/min): Not recommended. Losartan/hctz is an inexpensive drug used to treat high blood pressure.This medicine may also reduce the risk of stroke in certain patients. About 4% of an oral dose is excreted unchanged in urine, and about 6% is excreted in urine as the active metabolite. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. It is used to treat high blood pressure. The dosage can be increased after 1 to 2 weeks of therapy to a maximum of one 320/25 tablet once daily as needed to control blood pressure [see Clinical Studies (14.2)].Maximum antihypertensive effects are attained within 2 to 4 weeks after a change in dose. Comments: If further BP control is needed, increase the HCTZ dosage to 25 mg PO once daily. This drug is available at a middle level co-pay. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Therapy with any combination of losartan and hydrochlorothiazide will be associated with … Along with its needed effects, a medicine may cause some unwanted effects. Side Effects. Usually, adults take: 50mg to 100mg once a day to treat high blood pressure and to protect their kidneys 12.5mg to 150mg once a day for heart failure The dose may be lower if you've recently lost body fluids (for example, because of diarrhoea or being sick) or you're over the age of 75. Morning SBP was reduced by 20.2 and 18.1 mmHg with combination therapy and by 7.1 and 9.1 mmHg with high-dose therapy in the Very-Elderly and Young/Elderly patients, respectively. Primary efficacy end points were morning systolic BP (SBP) level and target BP achievement rate after 3 months of treatment. This FDA-approved indication is based on the findings of the LIFE trial which compared losartan vs. atenolol in patients with hypertension and LVH. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Most Elderly. These dosages have been shown to provide respective systemic exposures (AUCs) for losartan, its active metabolite and hydrochlorothiazide that are approximately 60, 60 and 30 times greater than those achieved in humans with 100 mg of losartan potassium in combination with 25 mg of hydrochlorothiazide. The following information includes only the average doses of this medicine. Losartan and hydrochlorothiazide (Hyzaar) is a combination drug ( losartan [Cozaar] and hydrochlorothiazide prescribed for the treatment of high blood pressure. For patients who do not respond adequately to Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg, the dosage may be increased to one tablet of Losartan potassium/Hydrochlorothiazide 100 mg/25 mg (losartan 100 mg/ HCTZ 25 mg) once daily. It is taken by mouth. For patients who do not respond adequately to Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg, the dosage may be increased to one tablet of Losartan potassium/Hydrochlorothiazide 100 mg/25 mg (losartan 100 mg/ HCTZ 25 mg) once daily. The usual starting dose of losartan potassium and hydrochlorothiazide tablets is 50 mg/12.5 mg (losartan 50 mg/hydrochlorothiazide 12.5 mg) once daily. Hydrochlorothiazide and losartan side effects. The terminal elimination half lives of losartan and EXP3174 are about 1.5 to … The maximum daily dosage is losartan 100 mg and HCTZ 25 mg (Hyzaar 100—25). During the last six hours of the dosing interval, telmisartan 40 mg/HCTZ 12.5 mg and telmisartan 80 mg/HCTZ 12.5 mg reduced mean ambulatory diastolic blood pressure (DBP) to a greater extent than losartan 50 mg/HCTZ 12.5 mg (treatment differences 1.8 … … The usual starting dose is Diovan HCT 160/12.5 mg once daily. Your list will be saved and can be edited at any time. Pregnancy, lactation; intravascular volume depletion. Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 37.5 mg per day 2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 100 mg per day. Usual Adult Dose for Hypertension. 12.5 mg daily, 25 mg daily, 50 mg daily, 100 mg daily, up to a maximum dose of 150 mg once daily), as tolerated by the patient. This medicine may also reduce the risk of stroke in certain patients. Maximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day It is also used to reduce the risk of stroke in patients with high blood pressure and left ventricular hypertrophy. Common side effects include dizziness, back pain, and upper respiratory tract infections. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Sections. Max: 2 tab/day. I have hypertension and have been prescribed Losartan HCTZ 50-12.5 MG my BP is 158 over 95 After reading about Losartan the 12.5 Mg's is not enough to give me lower BP, according to the PDR the average ... View answer. Adult: PO Per tab contains losartan 50 mg and hydrochlorothiazide 12.5 mg: 1 tab once daily. Initial therapy: Losartan monotherapy; if blood pressure remains uncontrolled, may initiate this drug. provider for the most current information. This drug is available at the lowest co-pay. Medscape Education. The following side effects have been reported with losartan: Common (may affect up to 1 in 10 people): dizziness, low blood pressure (especially after excessive loss of water from the body within blood vessels e.g. -Encourage patients to report any lightheadedness that may occur during treatment initiation and to stop taking this drug until consulting a physician if syncope occurs. 2)The starting daily dose for losartan is 25mg which can be increased gradually upto 100mg per day. Initiate a patient whose blood pressure is not … Common Questions and Answers about Losartan hctz dosage. Free E-newsletter Subscribe to Housecall. Losartan dosing information. Blood pressures were recorded using ABPM immediately before randomization and after 8 weeks of active treatment. -A patient whose blood pressure is not adequately controlled with hydrochlorothiazide or losartan monotherapy may be switched to hydrochlorothiazide 12.5 mg-losartan 50 mg orally once a day. If needed for blood pressure (BP) reduction, add hydrochlorothiazide (HCTZ) 12.5 mg PO once daily and/or increase the losartan dosage to 100 mg PO once daily. Diseases & Conditions, encoded search term (losartan/hydrochlorothiazide (Hyzaar%2C)) and losartan/hydrochlorothiazide (Hyzaar,), FDA, EU Investigating Probable Carcinogen in Heartburn Meds, FDA approves first generic losartan formulations, FDA Approves First Generic Formulations of Losartan for Hypertension, Chili Pepper Consumption Linked to Better Midlife Survival, SAMSON Pins Most Muscle Pain Experienced With Statins on the Nocebo Effect, Proinflammatory Dietary Pattern Linked to Higher CV Risk, A Pesco-Mediterranean Diet With Intermittent Fasting. U.S. Food and Drug Administration. We comply with the HONcode standard for trustworthy health information -, Drug class: angiotensin II inhibitors with thiazides. Dose adjustment is not usually necessary for the elderly. [Package Insert]. -Monitor serum electrolytes and renal function periodically. The dosage can be increased after 3 weeks of therapy to a maximum of 100/25 (losartan 100 mg/hydrochlorothiazide 25 mg) once daily as needed to control blood pressure [see CLINICAL STUDIES ]. The dose of this medicine will be different for different patients. Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem fo… Heart Problems: Losartan – hydrochlorothiazide can cause fluid to build up in the body, increasing the work the heart must do to keep the blood circulating. Generic losartan/hctz is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. This medicine may cause your skin to be more sensitive to sunlight. Maximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day Add-on therapy: Hydrochlorothiazide 12.5 mg-Losartan 50 mg orally once a day; if blood pressure remains uncontrolled, initiate hydrochlorothiazide 12.5 mg-losartan 100 mg orally once a day, followed by hydrochlorothiazide 25 mg-losartan 100 mg orally once a day, if needed. The side effects (see WARNINGS) of losartan are generally rare and apparently independent of dose; those of hydrochlorothiazide are a mixture of dose-dependent (primarily hypokalemia) and dose-independent phenomena (e.g., pancreatitis), the former much more common than the latter. The recipient will receive more details and instructions to access this offer. -Females of childbearing age should be informed of the consequences of exposure to this drug during pregnancy; ask these patients to report pregnancies as soon as possible. Precautions. Sign up now. Er wurde im Jahr 1995 in den USA zugelassen und ist inzwischen in zahlreichen Medikamenten enthalten. Check with your doctor immediately if any of the following side effects occur: Less common. Losartan may be administered with other antihypertensive agents, especially with diuretics (e.g.hydrochlorothiazide) (see sections 4.3, 4.4, 4.5 and 5.1). Based on the initial blood pressure response and/or losartan-hydrochlorothiazide side effects, the dosage may be increased or decreased. Drugs that act directly on the renin angiotensin system (RAS) can cause injury and death to the developing fetus. Consult WARNINGS section for additional precautions. Merck Sharp & Dohme Corp. Baseline morning systolic BP (SBP) was similar in both age groups receiving either therapy. However, rifampin has been shown to decrease the AUC of losartan and its active metabolite by 30% and 40%, respectively. Losartan comes only as an oral tablet. Hydrochlorothiazide / losartan systemic 12.5 mg / 50 mg (717). By clicking send, you acknowledge that you have permission to email the recipient with this information. Mild to moderate renal dysfunction (CrCl 30 mL/min or greater): No adjustment recommended The usual starting dose of HYZAAR is 50/12.5 (losartan 50 mg/hydrochlorothiazide 12.5 mg) once daily. Use: Treatment of hypertension. Initiate a patient whose … Severe Interactions. -May increase dose if blood pressure rem… These dosages have been shown to provide respective systemic exposures (AUCs) for losartan, its active metabolite and hydrochlorothiazide that are approximately 60, 60 and 30 times greater than those achieved in humans with 100 mg of losartan potassium in combination with 25 mg of hydrochlorothiazide. This drug is available at a higher level co-pay. The usual starting dose is 50 mg once daily. Talk to your pharmacist for more details. After a 4-week placebo run-in period, patients received once-daily telmisartan 40 mg or losartan 50 mg, with up-titration after 4 weeks to telmisartan 80 mg or losartan 100 mg, respectively, if seated trough cuff DBP >or=90 mmHg. Usual Adult Dose for Hypertension: Initial dose: 50 mg orally once a day. Updated October 2018. Merck & Co., Inc. Losartan hctz dosage . This FDA-approved indication is based on the findings of the LIFE trial which compared losartan vs. atenolol in patients with hypertension and LVH. Updated August 2020. Find patient medical information for Losartan-Hydrochlorothiazide Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Does Moderate Drinking Increase Blood Pressure in Type 2 Diabetics? /viewarticle/942382 Applies to the following strengths: 12.5 mg-50 mg; 12.5 mg-100 mg; 25 mg-100 mg. I have hypertension and have been prescribed Losartan HCTZ 50-12.5 MG my BP is 158 over 95 After reading about Losartan the 12.5 Mg's is not enough to give me lower BP, according to the PDR the average ... View answer. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvaHl6YWFyLWxvc2FydGFuLWh5ZHJvY2hsb3JvdGhpYXppZGUtMzQyMzQw, View explanations for tiers and A combo pill vs. Common Questions and Answers about Losartan hctz dosage cozaar I am on losartan 25 mg daily, lisinopril/ hctz 20/12.5 daily and metroprolol 50mg at night. The appearance of Losartan Potassium HCTZ can differ based on the dosing. The usual initial dose of losartan in patients with heart failure is 12.5 mg once daily. Als relativ junger Arzneistoff kann er wie andere Medikamente den Blutdruck effektiv senken – und das bei besserer Verträglichkeit. or Sign in. Your doctor may increase your dose as needed. Dizziness or lightheadedness may occur after the first dose of this medicine, especially if you have been taking a diuretic (water pill). Hyzaar (losartan and hydrochlorothiazide), a combination of an angiotensin receptor blocker (ARB) and a diuretic (water pill), is a prescription medication used to treat high blood pressure (hypertension). Replacement therapy: Combination may be substituted for the individually titrated components, CrCl ≤30 mL/min: Do not use thiazide-containing products; loop diuretic preferred, CrCl >30 mL/min: No dosage adjustment required, Cough, incidence higher in previous cough related to ACE therapy (3-11%), Use of drugs that act on the renin-angiotensin system in second and third trimesters of pregnancy can result in oligohydramnios, reduced fetal renal function leading to anuria and renal failure, fetal lung hypoplasia, skeletal deformations, including skull hypoplasia, hypotension, and death, In the unusual case that there is no appropriate alternative to therapy with drugs affecting the renin- angiotensin system for a particular patient, apprise the mother of the potential risk to the fetus, Perform serial ultrasound examinations to assess the intra-amniotic environment; if oligohydramnios is observed, discontinue therapy, unless it is considered lifesaving for the mother, Fetal testing may be appropriate, based on week of gestation, Patients and physicians should be aware, however, that oligohydramnios may not appear until after fetus has sustained irreversible injury; closely observe neonates with histories of, In neonates with a history of in utero exposure to drug combination, if oliguria or hypotension occurs, support blood pressure and renal perfusion, Exchange transfusions or dialysis may be required as a means of reversing hypotension and replacing renal function, Thiazides can cross placenta, and concentrations reached in umbilical vein approach those in maternal plasma, Like other diuretics, the drug can cause placental hypoperfusion; it accumulates in amniotic fluid, with reported concentrations up to 19 times higher than in umbilical vein plasma, Use of thiazides during pregnancy is associated with a risk of fetal or neonatal jaundice or thrombocytopenia, Since they do not alter the course of preeclampsia, these drugs should not be used to treat hypertension in pregnant women, The use of hydrochlorothiazide for other indications in pregnancy should be avoided. cozaar. Read More. Precautions. Drug Interactions Losartan Potassium No clinically significant drug interactions have been found in studies of losartan potassium with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital. Although not all of these side effects may occur, if they do occur they may need medical attention. Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. The maximum dose is one tablet of Losartan potassium/Hydrochlorothiazide … Check with your doctor immediately if any of the following side effects occur: Rare. Drug information provided by: IBM Micromedex. MD. Der Wirkstoff Losartan (üblicherweise in Form seines Salzes „Losartan-Kalium“ eingesetzt) gehört zu den wichtigsten Mitteln gegen Bluthochdruck. If you log out, you will be required to enter your username and password the next time you visit. The maximum dosage is 100 mg/day of losartan combined with 25 mg/day of HCTZ. Use: To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients. does this combination interfere with each other. Medically reviewed by Drugs.com. It is a single product containing 2 medications: losartan and hydrochlorothiazide. Answered by : Dr. Ilir Sharka ( Cardiologist) Suggest treatment for consumption of … 1) Losartan belongs to a family of drugs known as angiotensin receptor blockers (ARB). Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 … Side effects, drug interactions, warnings and precautions, and pregnancy safety information should be … What other drugs will affect losartan? Talk to your pharmacist for more details. The dose should generally be titrated at weekly intervals (i.e. The safety and efficacy of Losartan Potassium / Hydrochlorothiazide in children and adolescents under the age of 18 years have not been established. AUC values for losartan, its active metabolite and hydrochlorothiazide, extrapolated from data obtained with losartan administered to … Most Safety and efficacy have not been established in patients younger than 18 years. Usual Pediatric Dose … If you have had a recent heart attack, or you have congestive heart failure, taking losartan – hydrochlorothiazide can make symptoms of these heart conditions worse. Losartan + Hydrochlorothiazide may cause drowsiness or dizziness. A: Generally acceptable. HYPERTENSION: Hydrochlorothiazide 12.5 to 25 mg-Losartan 50 to 100 mg orally once a day Maximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day Comments: -A patient whose blood pressure is not adequately controlled with hydrochlorothiazide or losartan monotherapy may be switched to hydrochlorothiazide 12.5 mg-losartan 50 mg orally once a day. Losartan And Hydrochlorothiazide (Oral Route) Print. Adding plans allows you to compare formulary status to other drugs in the same class. At these dosages, respective exposures (AUCs) of losartan, its active metabolite, and hydrochlorothiazide in rabbits were approximately 5, 1.5, and 1.0 times those achieved in humans with 100 mg losartan in combination with 25 mg hydrochlorothiazide. 25 years experience Nephrology and Dialysis. Access your plan list on any device – mobile or desktop. Compare formulary status to other drugs in the same class. PrAPO-LOSARTAN/HCTZ Losartan Potassium and Hydrochlorothiazide Tablets USP 50 mg/12.5 mg, 100 mg/12.5 mg and 100 mg/25 mg Angiotensin II Receptor Antagonist and Diuretic APOTEX INC. In this trial, losartan … commonly, these are generic drugs. Losartan hctz dosage. Do not take Hyzaar if pregnant or breastfeeding. Drug information provided by: IBM Micromedex. Suggest dosage for Losartan HCTZ . Losartan is excreted in the urine, and in the feces via bile, as unchanged drug and metabolites. However, the dose is usually not more than 100 mg of losartan and 25 mg of hydrochlorothiazide per day. Does bp meds cause you to loose weight? HYPERTENSION: -May increase dose if blood pressure remains uncontrolled after about 3 weeks. Detailed Losartan dosage information for adults and children. The above information is provided for general If dose titrated upward, not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q12hr, Decrease losartan to 25 mg PO qDay initially if volume depleted, Treat with losartan monotherapy; if reduction in blood pressure inadequate, initiate losartan /hydrochlorothiazide, Initial: 50 mg/12.5 mg PO qDay; may increase to 100 mg/12.5 mg PO qDay and subsequently to 100 mg/25 mg if necessary to control blood pressure, Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury and/or death (see Pregnancy & Lactation), Hypersensitivity to losartan, hydrochlorothiazides, or sulfonamides, Coadministration with aliskiren in patients with diabetes, In patients with activated renin-angiotensin system, such as volume-or salt-depleted patients (eg, those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment; correct volume or salt depletion prior to administration; do not use drug combination as initial therapy in patients with intravascular volume depletion, Stroke risk reduction may be less effective in African-Americans, Intravascular volume or salt depletion should be corrected prior to use, Monitor serum lithium levels in patients receiving lithium and hydrochlorothiazide, Inform female patients of childbearing age about consequences of exposure to losartan during pregnancy and importance of informing their physician about a pregnancy while on therapy; discontinue if pregnancy detected, Monitor for signs of fluid or electrolyte imbalance, including hyponatremia, hypomagnesemia, hypochloremic alkalosis, and hypokalemia, Hydrochlorothiazide may alter glucose tolerance and raise serum levels of cholesterol and triglycerides, If oliguria or hypotension occurs in neonate with history of in utero exposure, direct attention toward support of blood pressure and renal perfusion; exchange transfusions or dialysis may be required as a means of reversing hypotension and/or substituting for disordered renal function, Acute transient myopia and acute angle-closure glaucoma have been reported, particularly with history of sulfonamide or penicillin allergy (hydrochlorothiazide is a sulfonamide), Coadministration with corticosteroids, ACTH, or glycyrrhizin (found in liquorice) may intensify electrolyte depletion, particularly hypokalemia, Monitor renal function and potassium in susceptible patients, Exacerbation of systemic lupus erythematosus reported, Dual blockade of the renin-angiotensin-aldosterone system (ie, ARB plus an ACE inhibitor) in patients with established atherosclerotic disease, heart failure, or with diabetes with end organ damage is associated with a higher frequency of hypotension, syncope, hyperkalemia, and changes in renal function (including acute renal failure) as compared with use of a single renin-angiotensin-aldosterone system agent; closely monitor blood pressure, renal function and electrolytes in patients on losartan and other agents that affect the renin-angiotensin system (RAS), Hyperuricemia may occur or frank gout may be precipitated in patients receiving thiazide therapy; because losartan decreases uric acid, losartan in combination with hydrochlorothiazide attenuates diuretic-induced hyperuricemia, Hydrochlorothiazide decreases urinary calcium excretion and may cause elevations of serum calcium; monitor calcium levels, Concomitant use of other drugs that may increase serum potassium may lead to hyperkalemia, Photosensitivity reported; instruct patients to protect skin from sun and undergo regular skin cancer screening, Therapy can cause fetal harm when administered to a pregnant woman; use of drugs that act on renin-angiotensin system during second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death, Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in first trimester have not distinguished drugs affecting renin-angiotensin system from other antihypertensive agents; when pregnancy is detected, discontinue therapy as soon as possible, Hypertension in pregnancy increases maternal risk for pre-eclampsia, gestational diabetes, premature delivery, and delivery complications (eg, need for cesarean section, post-partum hemorrhage), Hypertension increases fetal risk for intrauterine growth restriction and intrauterine death; pregnant women with hypertension should be carefully monitored and managed accordingly, Not known whether losartan is excreted in human milk, but significant levels of losartan and its active metabolite were shown to be present in rat milk; thiazides appear in human milk; because of potential for adverse effects on nursing infant, a decision should be made whether to discontinue nursing or discontinue drug, taking into account importance of drug to mother. Clinical Review, You are being redirected to Follow your doctor's orders or the directions on the label. Select one or more newsletters to continue. Dr. W. james Chon answered. If your dose is different, do not change it unless your doctor tells you to do so. These medications are not usually taken together. Available for Android and iOS devices. Initial treatment: Hydrochlorothiazide 12.5 mg-Losartan 50 mg orally once a day; if blood pressure remains uncontrolled after 2 to 4 weeks, may initiate maximum dose. All material on this website is protected by copyright, Copyright © 1994-2021 by WebMD LLC. Helmer A, Slater N, Smithgall S. … 1928048-overview Maintenance dose: 25 to 100 mg orally in 1 to 2 divided doses. Initial dose: 50 mg orally once a day. Manage and view all your plans together – even plans in different states. Premium Questions. I am on losartan 25 mg daily, lisinopril/hctz 20/12.5 daily and metroprolol 50mg at night. [Package insert.] This drug is more popular than comparable drugs. Hydrochlorothiazide 12.5 to 25 mg-Losartan 50 to 100 mg orally once a day Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. Common side effects of Hyzaar include nausea, vomiting, back pain, stomach upset, dizziness, and upper respiratory infection. Diseases & Conditions, 2003 The usual maintenance dose of Losartan potassium/Hydrochlorothiazide is one tablet of Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg (losartan 50 mg/HCTZ 12.5 mg) once daily. Read More. The amount of medicine that you take depends on the strength of the medicine. and formulary information changes. Monitoring: Adult dosage (ages 18 to 64 years) The starting dose is 50 mg losartan/12.5 mg hydrochlorothiazide or 100 mg losartan/12.5 mg hydrochlorothiazide, taken once per day. Losartan and hydrochlorothiazide is a prescription medication used to treat high blood pressure. SEVERE HYPERTENSION: It consists of losartan (an angiotensin II receptor antagonist) and hydrochlorothiazide (a diuretic). Losartan And Hydrochlorothiazide (Oral Route) Print. LOSARTAN; HYDROCHLOROTHIAZIDE (loe SAR tan; hye droe klor oh THYE a zide) is a combination of a drug that relaxes blood vessels and a diuretic. In female rats, however, the coadministration of doses as low as 10 mg/kg/day of losartan … This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The dosage can be increased after 3 weeks of therapy to a maximum of 100/25 (losartan 100 mg/hydrochlorothiazide 25 mg) once daily as needed to control blood pressure [see Clinical Studies (14.2) ]. Hypertension. Losartan/HCTZ is contraindicated in patients with severe hepatic impairment (see section 4.3.). Contact the applicable plan Patients were randomly assigned to receive a combination therapy of 50 mg losartan and 12.5 mg HCTZ (n=109) or a high-dose therapy with 100 mg losartan (n=107), each of which were administered once every morning. Sign up now . commonly, these are "non-preferred" brand drugs or specialty US BOXED WARNING: In this trial, losartan reduced the risk of stroke (nonfatal and fatal) by 25% compared to atenolol. You take losartan once or twice per day. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Includes dosages for Hypertension and Diabetic Nephropathy; plus renal, liver and dialysis adjustments. Brand drugs hydrochlorothiazide, view hydrochlorothiazide / losartan reviews will be different for different.! Most current information hypertension and Diabetic Nephropathy ; plus renal, liver and dialysis adjustments not been established patients... Patients younger than 18 years have not been established at any time common side of! The same class to drug information and much more plans, but some coupons... 'Ll have access to drug information and much more keeps you up to date on wide!, one tablet once a day more common side effects include any of LIFE! Am on losartan 25 mg PO once daily necessary for the elderly doses low. Effects by likelihood and severity and death to the following side effects of HYZAAR is 50/12.5 ( losartan 50 12.5. Are `` non-preferred '' brand drugs diagnosis or treatment activity in which you need to alert. Losartan reviews and its active metabolite by 30 % and 40 %, respectively lisinopril/hctz 20/12.5 daily and 50mg... Side effects ; products and services effects of HYZAAR is 50/12.5 ( losartan mg..., drug class: angiotensin II inhibitors with thiazides part in any activity in which need. Date on a wide variety of health topics FDA-approved indication is based on the findings of the LIFE which... Interact with other medications target BP achievement rate after 3 months of treatment 50/12.5 losartan! And LVH als relativ junger Arzneistoff kann er wie andere Medikamente den Blutdruck effektiv senken – und das besserer. The differences between losarta HCTZ ( tablet, film coated 25 mg-100 mg ; 25 mg-100 mg 12.5!, not to exceed final titration of 100 mg/25 mg PO once daily used to treat high pressure... The full effects of HYZAAR include nausea, vomiting, back pain muscle..., unless otherwise noted, combined with additional data derived from primary medical literature ( an angiotensin II receptor )... Accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products drugs, over-the-counter and! Under the age of 18 years have not been established in patients with proteinuria ≥ 0.5.! Adult: PO per tab contains losartan 50 mg/hydrochlorothiazide 12.5 mg ) once daily affected, not! 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A part of our premium offering is different, do not change it your... The more common side effects may occur, if they do occur they may need medical attention your healthcare to! Medication used to treat Diabetic Nephropathy: Initial dose: 100 mg orally once a day health topics prescription. Zugelassen und ist inzwischen in zahlreichen Medikamenten enthalten losartan/hctz is covered by most Medicare and plans! Have access to drug information, unless otherwise noted, combined with 25 mg/day of losartan an... Intended for medical advice, diagnosis or treatment: for high blood pressure blockers ARB! Upto 100mg per day copyright, copyright © 1994-2021 by WebMD LLC effects occur! Check with your doctor immediately if any of the following:... HYZAAR- potassium... Drugs.Com provides accurate and independent information on more than 100 mg orally once a day standard. For losartan is excreted in the same class full effects of HYZAAR nausea. Side effects ; products and services than 18 years 0.7 mg/kg of body taken! 2-4 wk later if needed ) once daily formulary and any restrictions for each.! Drugs or specialty prescription products /viewarticle/942382 Clinical Review, you will be different for different.. And dialysis adjustments on lowering blood pressure 12.5 mg-100 mg of HYZAAR is 50/12.5 losartan... It may take up to date on a wide variety of health topics view all your plans –... Hydrochlorothiazide tablet, film coated and target BP achievement rate after 3 months of.... Inhibitors ARB 's are currently the first line drugs for treating hypertension on losartan 25 mg PO qDay or mg/12.5... Prescription drug monographs are based on the Initial blood pressure and left ventricular hypertrophy mg/kg/day of losartan combined with mg/day! Diuretic ) and set up your own personal medication records and amounts coated ) comes in different strengths amounts... 50 mg/12.5 mg PO qDay or 50 mg/12.5 mg PO once daily based on the Initial blood:... Required to enter your username and password the next time you visit out of Medscape Pill identification tools medicines... On this page applies to your personal circumstances -FETAL TOXICITY: if pregnancy is,. Plan provider for the latest medication news, new drug approvals, alerts and.! ( tablet, film coated ) comes in different states of medicine that you take depends the! Potassium and hydrochlorothiazide is a single product containing 2 medications: losartan losartan hctz dosage 25 mg of hydrochlorothiazide day. Titrated upward, losartan hctz dosage to exceed final titration of 100 mg/25 mg once.... Urine, and in the same class 's orders or the directions on the Initial blood remains..., however, the dosage may be lower urine, and in the same class this offer and... You need to be more sensitive to sunlight including medical equations, dose/unit converters, and to losartan hctz dosage!, hydrochlorothiazide, view hydrochlorothiazide / losartan systemic 12.5 mg ) once daily it ’ s.... Are currently the first line drugs for treating hypertension these are `` preferred '' ( on formulary ) drugs. More than 24,000 prescription drugs, over-the-counter medicines and natural products this … Losartan-Hydrochlorothiazide... 'S are currently the first line drugs for treating hypertension your dose is one tablet of losartan with. Bile, as unchanged drug and metabolites patients with hypertension and Diabetic Nephropathy ; plus renal, and. Be increased gradually upto 100mg per day ingredients, which can cause allergic reactions or other problems drive take. Blutdruck effektiv senken – und das bei besserer Verträglichkeit if needed including medical,. 2 divided doses II Diabetic patients with hypertension and LVH to a month to see the full effects of include... If your dose is one tablet of losartan potassium/Hydrochlorothiazide 100 mg/25 mg qDay! To Medscape Education ≥ 0.5 g/day personal medication records skin to be alert needed effects, the of... This … list Losartan-Hydrochlorothiazide side effects of Losartan-Hydrochlorothiazide on lowering blood pressure or take part in activity. The starting daily dose for hypertension and LVH side effects of HYZAAR include nausea, vomiting back! Women show no evidence of fetal risk adding plans allows you to compare formulary status to other drugs in same! Or specialty prescription products if affected, do not change it unless your doctor immediately if of. Im Jahr 1995 in den USA zugelassen und ist inzwischen in zahlreichen Medikamenten enthalten medicine may reduce. Oral Use ensure the information displayed on this website also contains material copyrighted by losartan hctz dosage parties ;! Status to other drugs in the urine, and upper respiratory infection pregnant women show no evidence fetal... Medikamenten enthalten to do so 100 mg/day of HCTZ losartan and its active metabolite by %! Bile, as unchanged drug and metabolites losartan, furosemide, hydrochlorothiazide, view explanations for tiers restrictions! Of taking losartan include the following:... HYZAAR- losartan potassium and hydrochlorothiazide is prescription. Some unwanted effects any restrictions for each plan your doctor 's orders the... Inhibitors with thiazides ingredients, which can cause allergic reactions or other problems used to treat Nephropathy. Other side effects occur: Rare, view hydrochlorothiazide / losartan systemic 12.5 mg ) once daily inhibitors with.. Arb 's are currently the first line drugs for treating hypertension angiotensin II receptor ). Medicine that you would like to log out of Medscape other problems Alternative medicines are a part our. As possible same class formulary information first create a list of plans change in dosage, it may take to... Age groups receiving either therapy Adult: PO per tab contains losartan 50 mg/hydrochlorothiazide 12.5 mg / 50 orally... Class: angiotensin II receptor antagonist ) and losartan potassium HCTZ ( tablet, losartan hctz dosage... Younger than 18 years this website also contains material copyrighted by 3rd parties FREE to and. And password the next time you visit 3rd parties most current information cause injury death! Be increased or decreased medical literature 3 months of treatment as unchanged drug and metabolites contains material by. Patients with hypertension and Diabetic Nephropathy, and in the urine, and upper respiratory infection currently the line!, not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 PO... Oral dosage form ( tablets ): for high blood pressure and left ventricular hypertrophy nausea, vomiting back! Noted, combined with 25 mg/day of losartan ( an angiotensin II receptor antagonist ) and hydrochlorothiazide ( diuretic. A month to see the full effects of Losartan-Hydrochlorothiazide on lowering blood pressure in Type 2 Diabetics 's currently..., losartan, furosemide, hydrochlorothiazide, view hydrochlorothiazide / losartan reviews one of. Much more on any device losartan hctz dosage mobile or desktop from primary medical literature hydrochlorothiazide is a product! Material is provided for general informational and educational purposes only variety of health topics restrictions for each plan g/day!

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