(1968) Diseases of the chest. 27-05-2014 - Klebsiella pneumonia is refers to a pneumonia resulting from an infection from the organism Klebsiella pneumoniae. It is an important type of pneumonia because of its severity, high incidence of complications, and elevated mortality [1]. The 70 isolates were taken from diverse clinical specimens. The chest films of 58 patients with proved pneumonia due to Pseudomonas, Klebsiella, Enterobacter, Escherichia coli, Proteus, or Bacteroides were reviewed.Pseudomonas pneumonia was characterized by diffuse alveolar involvement with rapid progression to extensive macrocavitation. Massive necrosis (pulmonary gangrene) is a recognized complication. These infections are particularly a problem among neonates, elderly and immunocompromised individuals. Figure Klebsiella pneumoniae liver abscess cases (n=123) in an outpatient parenteral antibiotic therapy (OPAT) cohort in Singapore, 2006–11 (n=2229) View Large Image Figure Viewer; Download Hi-res image Download (PPT) Roughly 70% of patients with K pneumoniae abscesses were men. Massive necrosis (pulmonary gangrene) is a recognized complication. CT Appearance of Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae. There tends to be a higher prevalence in older patients with alcoholism and debilitated hospitalized patients 3. Volume: 260 Issue: 1 pp. Hansell DM. 1 - 5 Although single case reports discuss the clinical presentation of pneumonia caused by Escherichia coli or Actinobacillus spp., 6, 7 to the authors’ knowledge no large retrospective studies describe the … The disease is often overlooked in the Western physicians due to its rarity. Check for errors and try again. It has a high mortality rate of approximately 50% even with antimicrobial therapy. Klebsiella species cause a wide range of diseases including pneumonia, urinary tract infections (UTIs), bloodstream infections and sepsis. After that, a 6-week course of amoxicillin-clavulanate (1 g every 12 h) was substituted. Rev. 53 (4): 481-6. 2010;83 (994): 854-60. Moon WK, Im JG, Yeon KM et-al. Extensive right upper lobe consolidation, with bulging of the horizontal fissure. They are commonly found in the environment and in … 8. In comparison, cavitation is rare in pneumococcal pneumonia. Massive necrosis (pulmonary gangrene) is a recognized complication. Mosby Incorporated. Also, lobar expansion is not specific for Klebsiella infection. See additional information. The Brant and Helms Solution. Cavitary pulmonary disease. the Western countries, Klebsiella pneumoniae invasive syn-drome (KPIS) should be alerted when patients present atypi-cal vague symptoms including fever, chill, nausea, vomiting, and right upper quadrant tenderness. This occurs early and progresses quickly. 2000 Oct;63(10):721-8. Klebsiella pneumonia | Radiology Reference Article | Radiopaedia.org. Imaging of Diseases of the Chest. 129-138. Anat. Klebsiella pneumoniae renal abscess Zhonghua Yi Xue Za Zhi (Taipei). Hansell DM. [12,17] Aspiration pneumonia should always be suspected if the infiltrates are present bilaterally in the dependent or posterior portions of the lungs. CHEST Journal. These bacteria are harmless when they’re in … Coronavirus: ... 2 Division of Diagnostic Radiology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. 4. Diagnosis: Klebsiella pneumonia (aka Friedländer’s pneumonia) - Images, diagnosis, treatment options, review - Thoracic Imaging Case. (1882) Virchow Arch. Risk factors for Klebsiella pneumonia include alcoholism, diabetes mellitus, and COPD. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Ono A. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis. Pulmonary infection can also be classified into several radiologic and pathologic patterns according to its morphologic features. Invasive community-acquired infections, including pyogenic liver abscesses, caused by hypervirulent Klebsiella pneumoniae (hvKp) strains have been well recognized worldwide. Klebsiella pneumoniae was first described by a German microbiologist and pathologist Carl Friedländer in 1882. Radiology 2007. Klebsiella pneumoniae is a bacterium that normally lives inside human intestines, where it doesn't cause disease.. A report of 11 cases and appraisal of antibiotic therapy. There can be variable features on chest HRCT which can also depend on current other organisms. In the setting of pneumonia, infection with K. pneumoniae is confirmed by either sputum culture analysis, blood culture analysis or midstream urine depending upon the illness. ADVERTISEMENT: Supporters see fewer/no ads. Lippincott Williams &Wilkins. In nosocomial pneumonia, patchy bronchial pneumonia is the most common finding and is likely caused by Gram-negative pathogens, especially Pseudomonas or Klebsiella. … Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Clin. All rights reserved. Klebsiella pneumonia, also known as Friedländer pneumonia, refers to pneumonia resulting from an infection from the organism Klebsiella pneumoniae. Klebsiella pneumoniae(K. pneumoniae) is a Gram-negative, non-motile, capsulated, gas-producing enteric bacillus widely found in nature, and it belongs to the normal flora of the human oral cavity and intestine. Klebsiella pneumoniae is a Gram-negative bacteria and a well-known cause of community-acquired pneumonia, which accounts for less than 5% of all cases of pneumonia. © 2005 - 2021 WebMD LLC. 2008;21 (2): 305-33, table of contents. (2007) ISBN:B0011ZYZR2. The spectrum includes. Klebsiella pneumoniae is among the most common Gram-negative bacteria encountered by physicians worldwide and accounts for 0.5-5.0% of all cases of pneumonia 2. Results: The mean age was 58.7 years and the male to female ratio was 10:14. On CXR, consolidation is lobar and resembles streptococcus pneumonia. 7. 61-year-old woman with a long-standing history of alcohol abuse presented with a sudden onset of cough, pleuritic chest pain, dyspnea, fever, and rigors. Friedlander, C. Über die Pseudomyceten bei der acuten fibrinösen Pneumoniae. On CXR, consolidation is lobar and resembles streptococcus pneumonia. {"url":"/signup-modal-props.json?lang=us\u0026email="}. VCU Department of Radiology VCU Medical Center. There can b… Introduction . Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium that is found in the environment and has been associated with pneumonia in the alcoholic and diabetic patient population. Conversely, various pathogens give rise to identical radiologic findings; e.g., bronchopneumonia can be caused by, for example, Staphylococcus aureus, Klebsiella, Proteus, or Pseudomonas. This occurs early and progresses quickly. However, in general, the type of microorganism implicated in pneumonia can be identified (bacteria, viruses, or fungi). The Post-operative Abdomen - Surgicel … Seventy of Klebsiella pneumoniae isolates had been collected from some Hospitals in Baghdad city from October to December 2017. Klebsiella pneumoniae, a gram-negative organism, is an emerging common cause of PLA, particularly in patients with poorly controlled diabetes mellitus and without any pre-existing liver disease. Klebsiella is also responsible for a significant number of community-acquired infections. Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium.It appears as a mucoid lactose fermenter on MacConkey agar.. K. pneumoniae is found in the normal flora of skin, mouth and intestines, where it does not cause disease. Klebsiella species are a Gram-negative rod shaped bacteria belonging to the Enterobacteriaceae family. The past 3 decades have seen the emergence of an invasive liver abscess syndrome caused by Klebsiella pneumoniae that may manifest with metastatic infection to the eye, brain, or lung [1, 2]. Klebsiella pneumonia is a necrotizing process with a predilection for debilitated people. 1995;19 (2): 176-81. 87: 319. K. pneumoniaewas first discovered by Friedlander in 1882 and considered to be responsible for a severe form of lobar pneumonia. are commonly implicated as a cause of bacterial pneumonia in horses, but few reports describe the clinical presentation and progression of disease attributable to this organism. J Comput Assist Tomogr. by Wenlie Xie and Huixuan Jia. Hoffman NR, Preston FS. E.Brant MW, A.Helms MC. (2009) ISBN:0723434964. Friedlander's pneumonia. This occurs early and progresses quickly. The presence of gram-negative rods in Gram-stained smears suggests Klebsiella; they maybe capsulated and non-sporing. The bacterium typically colonizes human mucosal … Chronic Klebsiella pneumonia: a rare manifestation of Klebsiella pneumonia. Microbiol. Recommended Articles. 01 Jul 2011 Radiology. Volume: 242 Issue: 3 pp. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Complications of Klebsiella pneumonia: CT evaluation. bulging of the horizontal fissure in this case) is less common nowadays with modern antibiotic treatment. Klebsiella pneumoniae- Pathogenicity and Clinical Manifestations. Acute Klebsiella pneumoniae pneumonia alone and with concurrent infection: comparison of clinical and thin-section CT findings. Since 1950, 76 proved cases of pneumonia due to Staphylococcus aureus have been seen at the Los Angeles County Hospital. K. pneumoniae is also a well-known cause of community-acquired pneumonia. WebMD does not provide medical advice, diagnosis or treatment. Gadkowski LB, Stout JE. Okada F, Ando Y, Honda K et-al. {"url":"/signup-modal-props.json?lang=us\u0026email="}. 6. ; Material is inoculated into blood agar and Mac Conkey agar medium and incubated aerobically. Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae: US Appearance and Aspiration Findings. 5. Among these, sporadic hvKp-related community-acquired pneumonia (CAP) is an acute-onset, rapidly progressing disease that can likely turn fatal, if left untreated. The three most common patterns are lobar pneumonia, bronchopneumonia, and interstitial pneumonia. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. Continuous improvement of the lesion was found on follow-up chest X-rays. 3. Chronic Klebsiella pneumonia was diagnosed and ceftazidime was changed to ceftriaxone 1 g every 12 h for 2 weeks. This organism can cause extensive pulmonary necrosis and frequent cavitation 1. There has been a considerable increase in the incidence of this type of pneumonia beginning in 1954 and reaching a peak in 1956, with 21 cases. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. 1. Lobar expansion (e.g. Unable to process the form. Imaging of Diseases of the Chest. Unable to process the form. The hypervirulence of these novel community-acquired strains is mediated in part by their hypermucoviscous phenotypes associated with K1 and K2 capsule serotypes [ 3–5 ]. The organism Klebsiella pneumoniae was first described by German microbiologist Carl Friedländer (1847-1887) in 1882, in a series of patients with Klebsiella pneumonia 7,8. Check for errors and try again. It is not possible radiologically to pinpoint the causative organism. (2009) ISBN:0723434964. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). 769-776. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Authors S ... diagnostic radiology studies, therapeutic modalities and risk factors associated with mortality were studied. All K. pneumoniae isolates were identified based on API 20 E and Vitek2 compact system. Mosby Incorporated. Necrotizing pneumonia can occur as a complication 6. Sputum analysis grew Klebsiella pneumoniae. Often there can be extensive lobar opacification with air bronchograms. Path. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). K pneumoniae monomicrobial liver abscesses were associated with diabetes mellitus (P <.001), higher blood glucose levels at admission (P <.05), predominantly solid US appearances (P <.001), irregular or indistinct lesion margins (P <.05), less than 2 mL of pus aspirated (P <.001), and longer duration of antibiotic treatment (P <.05). Klebsiella pneumonia usually results from aspiration of colonizing oropharyngeal microbes into the lower respiratory tract. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. Case of the Week: August 27-September 3, 2009. Klebsiella pneumoniae (K. pneumoniae) are bacteria that normally live in your intestines and feces. Often there can be extensive lobar opacification with air bronchograms. Nineteen cases were seen in the first half of 1958. Radiology 2011. Klebsiella pneumoniae is a Gram-negative bacillus with worldwide distribution that usually causes respiratory and urinary tract infections, ... Four weeks after admission, following discussion with Radiology, a thoracic CT scan was performed for subsequent biopsy of one of the pulmonary lesions. To retrospectively compare the computed tomographic (CT) features of liver abscesses caused by Klebsiella pneumoniae with those caused by other bacterial pathogens. Antibiotics sensitivity test was carried out toward 10 antibiotics using discs diffusion method. 2. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Klebsiella spp. 2011;140 (4_MeetingAbstracts): . Less common forms of infection include cellular bronchiolitis, septic embolism, miliary infection, and lung abscess. Br J Radiol. 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